The Top Probiotics For Better Gut Health of 2024

By: DTW Health Advisory Board

This website is owned and operated by Stingray Direct. Stingray Direct is the distributor of Stonehenge Health products and may receive compensation from companies featured when you purchase through the provided links.

what to avoid?

what to look for?

how to pick a good probiotic supplement & avoid the junk

With so many options, it seems many of us might still be unclear about what to look for in a quality probiotic supplement. To help cut through the clutter, we have compiled months of research about the key probiotic strains that have been shown in studies to offer real benefits.

This short guide will help you know what to look for and what to avoid so you can make an informed decision regarding your probiotic supplement needs. We will also list out the top 5 probiotic supplements sold today that we researched so you don’t have to.

Let’s take a moment to understand precisely how probiotics work and why it’s essential to add them to your daily routine.

Probiotics: What Are They All About?

Within our intestines is a complex world known as the gut microbiome, which comprises thousands of different types of bacteria, fungi, and even viruses. Some of the bacteria can offer significant health benefits, while others can be harmful.

A quality probiotic pill should contain a potent dose of friendly bacteria in different varieties. When consumed, probiotics will make their way to your colon, attach to the walls of your intestine, and begin to colonize. Assuming you take the right kind of probiotic that has clinically studied strains, as they grow, they can help with better digestion, support the absorption of minerals and nutrients, and help rid the body of toxins and waste.

a good probiotic supplement works to:

Support Healthy Weight^2-5

Help ease Gas, Bloating, & Promote Regularity^6-10

Strengthen Gut Wall Integrity¹¹

Support Digestion¹²

Ease Menopause¹³

Improve Mood^14,15

Support Immune System Funtion^16,17

Promote Better Candida Balance¹⁸

Title

3 Things To AVOID

When Buying A Probiotic Supplement

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1. lack of strain diversity

Clinical studies have shown that specific probiotic strains can help with particular health concerns.19,20 While the human gut contains thousands of different bacterial strains, most probiotics only include a few generic Lactobacillus or Bifidobacterium strains. Look for a probiotic that has at least 16 unique strains to support proper microbiome balance.

2. cheap generic strains

Store shelves are filled with brands selling probiotics, listing cheap generic forms of popular strains on their labels. Research shows that not all probiotic strains produce the same results, even if they have the same name.²¹ Like most things in life, it all comes down to the details.

A high-quality brand will list the strain and a combination of letters and numbers, such as L. acidophilus La-14TM, known as a substrain. This unique identifier tells you that one or more clinical studies back the strain being used. We advise you avoid probiotics that don’t list substrains, as that could be a warning sign that low-quality, generic, and possibly ineffective strains are used in the formula.

3. plastic bottles

Moisture vapor transmission rate (MVTR) studies on probiotics packaged in plastic bottles have shown that they can allow too much moisture to enter, causing lower strain survival rates and a shorter shelf life overall.²²

Don’t throw away your hard-earned money on probiotics in cheap plastic bottles that can allow harmful elements to enter during storage and shipping, risking your probiotics arriving dead at your doorstep.

Which Probiotics Strains

Are Best?

When it comes to probiotic strains, not all are created equal. And while there are as many as 500 different strains, only a handful have substantial research supporting health benefits.23 Below are the ones we feel can give you real results.

1. Lactobacillus Gasseri

Healthy Weight Support: A review of over a dozen human randomized controlled trials concluded that L. gasseri supports healthy weight management. Other studies have shown that this strain supports the reduction of fatty tissue and promotes ideal metabolism.^24-27

Bone Density: Shown to have positive effects on menopause by increasing bone mineral density and easing discomfort sensitivity.²⁸

2. Lactobacillus Rhamnosus

Occasional Irregularity and Watery Stools: Helps strengthen the gut lining and promotes a balanced microbiome which helps with acute watery stools.^29-32

Vaginal Health: Helps to promote balanced vaginal flora and normal candida growth.^33-36

Mood: Eases stress and boosts mood by promoting better GABA function, which communicates with the brain and may produce a calming effect.^37,38

3. Lactobacillus Reuteri

Leaky Gut: Helps to strengthen and repair the intestinal barrier, which, when function is compromised, can allow harmful bacteria to enter the body and cause acute bloating, occasional constipation, excess gas and discomfort, and food sensitivities.³⁹

Urinary Tract Health: Provides female support to strengthen and protect the Urinary Tract function.⁴⁰

Dental Health: As one of the few probiotics found in the mouth, studies have shown it helps balance oral flora which when unchecked can promote tooth decay.⁴¹

H.Pylori Defense: May help with digestive health and balance the levels of Helicobacter pylori (H. pylori), a bacteria that researchers have linked to digestive concerns.⁴²

4. Lactobacillus Acidophilus

Dairy Defense: It produces lactase, the enzyme needed to break down the sugar in milk called lactose, which helps ease digestive concerns.⁴³

Mineral Absorption: Helps to promote the absorption of minerals such as iron, calcium, and magnesium.^45,45

Vaginal Health: Produces high lactic acid levels, promoting an acidic environment in the vagina necessary to keep proper levels of vaginal flora.⁴⁶

5. Bifidobacterium Bifidum

Regularity: Promotes regular and smoother bowel movements by supporting the production of mucus in the colon.⁴⁷

Promote better immune health: By promoting normal histamine production which can help ease seasonal allergies.⁴⁸

***Stack Tip: Look for a formula that pairs L. Acidophilus with B. Bifidum, as they have been shown to work well together to populate the gut with good bacteria.

5. Bifidobacterium Longum

Liver Health: Human clinical studies show that B. longum paired with the prebiotic FOS plays a beneficial role in supporting liver health.^49,50

Immune Support: Helps to strengthen the body’s natural defenses and promote respiratory tract health.^51,52

Title

Top 4 Essential Criteria For A

Quality Probiotic Supplement

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We spent months researching probiotics and gathering user feedback. There are specific aspects that differentiate high-quality probiotics from generic ones. Below are the 4 most essential criteria to consider when deciding on which probiotic brand is best for your needs.

#1 High CFU Counts

You can have the highest quality strains, but if you don’t have them in a potent enough dose, they will not be very effective amongst the trillions of other bacteria in the gut. The quantity aspect of a probiotic is measured in Colony Forming Units (CFUs). Look for a formula that contains a minimum of 55 Billion CFUs per dose.

#2 Clinically Studied Strains

Supply chain issues and inflationary pricing have driven many manufacturers to pursue more readily available cheap generic strains that have not been proven effective in clinical testing.

Check the supplement facts section of a probiotic label to see if the name has the trademark ™ or registered symbol ® next to each strain’s substrain. This symbol is a good indication that the strain is from a top-quality brand and has probably undergone clinical testing. Remember, not all strains perform the same, even if they have the same general name.

#3 Prebiotics

Once probiotics make their way to your gut, they begin to feed off prebiotics, a fiber-based form of food needed to help them survive, grow, and populate. We suggest looking for a formula that explicitly includes the prebiotic NutraFlora^® which has twenty years of research and over 200 studies proving it helps stimulate the growth of probiotics.⁵³ Don’t just take a brand’s word that they include a prebiotic. Check the back of their label to make sure it is a NutraFlora^® branded prebiotic and not some generic form in their list of ingredients.

#4 Glass Bottle

Moisture is the number one element that can destroy the stability of probiotics, even if freeze-dried.⁵⁷ Studies have shown that glass bottles are the best packaging for probiotics as they allow for nearly zero moisture to enter.⁵⁸ For maximum shelf life and effectiveness, look for a probiotic that comes in a dark amber glass bottle, as only dark glass can keep out moisture and light.

Title

How We Evaluated Our Probiotic Supplement Recommendations

clinically-studied, quality probiotic strains

We looked for formulas that contain probiotics that have undergone clinical testing with research-backed results.

strain diversity

We searched for formulas with high-strain diversity to help increase good bacteria in the gut.

High CFU Counts (Live Probiotic Cultures)

High CFUs counts help ensure the effectiveness of a formula.

added prebiotic support

We looked for a well-rounded formula that includes prebiotics to help probiotics flourish.

2024 Probiotic Buying Guide

Advertisement sponsored by Stingray Direct, the distributor of Stonehenge Health products.

stonehenge health^®
dynamic biotics

researched & approved

Pros

16 Diverse Probiotic Strains & 55 Billion CFUs

Endorsed by a Doctor Specializing in Digestive Health

Includes ALL Top-6 Strains & Prebiotic NutraFlora^®

Dark Amber Glass Bottle for light and moisture protection

Clinically Studied sub-strains listed on the label

Vegetarian acid-resistant capsules

Non-GMO, Vegetarian, Gluten Free, and No Preservatives

Verified 90-day 100% money-back return policy

Cons

Often out of stock due to high demand

why we approved

Stonehenge Health’s Dynamic Biotics is the first recommended brand on this list because this formula contains a potent 55 Billion CFU dose of 16 diverse clinically studied strains, including all six of the essential strains L. Gasseri, L. Rhamnosus, L. Reuteri, L. Acidophilus, B. Bifidum, and B. Longum.

Dynamic Biotics’s label lists each probiotic and its unique identifying substrain allowing for maximum traceability and instilling confidence that one or more clinical studies back each strain. We were happy to see that this formula includes the prebiotic NutraFlora® to help nourish the probiotics supporting their survival and growth.

In reviewing dozens of probiotic brands, we found that most package these light and moisture-sensitive live cultures in cheap plastic bottles, increasing the risk you will receive a probiotic that is dead on arrival. We liked that Stonehenge Health uses a dark amber glass bottle to protect its probiotics and improve survivability. With the correct probiotics and prebiotics at the proper CFU strength, Dynamic Biotics has what it takes to help support digestive and immune health and promote a healthy gut microbiome.

We were able to verify that Stonehenge Health’s formula does not contain any synthetic fillers or artificial ingredients, is non-GMO, and uses vegetarian capsules. Stonehenge Health backs its products with a no-questions-asked, 90-day money-back guarantee and is one of the few brands endorsed by a board-certified doctor specializing in digestive health. We also like that they offer customers discounts on bundles. Click on the link below to see their current specials.

*Please refer to the manufacturer’s product website for detailed information.

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renew life
extra care probiotics

researched

Pros

Title

12 Diverse Probiotic Strains

50 Billion CFUs

Clinically Studied sub-strains

Veggie caps, Non-GMO, Gluten & Soy Free

Cons

Title

Only includes 2 of the Top-6 Strains

Does not include any Prebiotics

Plastic bottle instead of glass

User complaints new formula not as effective

Quality control concerns about safety seals

Limited return policy

Renew Life Extra Care Probiotics contains 12 varieties of strains and lists each substrain on the product label. We were happy to see that each dose is 50 billion CFUs but were disappointed that the formula lacked prebiotics.

While Renew Life has a decent diversity of strains, it fell short of our recommended minimum of 16 strains. We were perplexed why this brand only included 2 of the top-6 strains, L. Rhamnosus and L. Acidophilus, leaving out the highly researched and effective L. Gasseri, L. Reuteri, B. Bifidum, and B. Longum.

This product comes in vegetarian capsules, great for health-conscious users. Still, the inclusion of medium-chain triglycerides in the formula may be the reason behind reports of digestive discomfort by some users. A common and growing complaint amongst other users is that a recent change in the formula has rendered the product less effective.

Renew Life offers a 60-day money-back guarantee, but we would have preferred to see a 90-day guarantee to allow more time for consumers to assess if it is right for them.

*Please refer to the manufacturer’s product website for detailed information. Renew Life is a registered trademark of RENEW LIFE FORMULAS, LLC

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florastor daily probiotics

researched

Pros

Title

Contains clinically researched strain Saccharomyces boulardii lyo CNCM I-745

Veggie caps, Non-GMO, & Gluten Free

Cons

Title

Only contains one clinically studied strain

Limited potency of 10 Billion CFUs

Contains dairy and No Prebiotics

No company guarantee or return policy

Florastror is a yeast-based probiotic with one clinically studied strain, Saccharomyces boulardii lyo CNCM I-745. Each capsule of Florastor contains 250 mg, which is equivalent to 5 Billion CFUs. A single dose is two capsules, 500 mg, for 10 Billion CFUs.

Studies on CNCM I-745 indicated positive results, especially for addressing antibiotic-induced diarrhea, but used doses of three to four capsules per day. Florastor’s suggested use is two capsules taken 1-2 times per day, a maximum of four capsules in a day, making a one-month supply of 60 to 120 capsules. Users have complained that Florastor only sells their product in 18, 20, 30, 50, and 100 counts, none of which is a one-month supply. This brand’s 100-count package costs $62, making it one of the most expensive probiotics we have researched.

This formula lacks the benefit of a diversity of strains and the potency of higher CFU strength to address broader digestive health concerns. A notable downside is that Florastor contains milk (lactose), eliminating those who are lactose intolerant. Reviews have been mixed from users, with some stating they did not get their desired results. Florastor does not have a guarantee policy listed on their site, leaving consumers to deal only with the refund/return policy from the retail store they purchased it in.

* Please refer to the manufacturer’s product website for detailed information. Florastor is a registered trademark of Biorganon SA.

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align probiotic

researched

Pros

Title

Contains one out of our top-6 strains

Veggie caps, Gluten & Soy Free

Cons

Title

Only contains one clinically studied strain

Limited potency of only 1 Billion CFUs

Contains unnecessary additives and fillers

Does not contain prebiotics

Limited 60-day return policy

Align Probiotic is a popular product thanks in part to their heavy television advertising. The formula contains a single clinically studied strain, Bifidobacterium Longum 35624™, formerly known as Bifidobacterium infantis or Bifantis. It has a limited potency of only 1 Billion CFUs per dose.

While we liked that this formula contains the strain B. Longum, one of our top-6 recommended strains, it is crucial to have a diverse array of strains. And so, we were disappointed to see Align was missing L. Gasseri, L. Rhamnosus, L. Reuteri, L. Acidophilus, and B. Bifidum. It also does not have any prebiotics, which is essential to aid the growth and survivability of probiotics in the gut.

Align’s inclusion of undesirable and potentially problematic additives in the product is an area of concern. One additive in particular, Titanium Dioxide, which makes their capsule a bright white color, is viewed as safe by the FDA but the European Union recently banned it. 59 The EU’s research has shown it may be a harmful carcinogen. Other additives include sucrose (sugar), propyl gallate, and gellan gum, which may cause gastrointestinal discomfort. This product also contains milk, eliminating those who are lactose intolerant. The return policy for Align Probiotics is limited to 60 days and is provided via a pre-paid card with funds that expire in six months, which is not as convenient as simply a refund to your credit card.

* Results are based on user-generated experiences with these products, and individual results may vary. Please refer to the manufacturer's product website for detailed information.

* Please refer to the manufacturer’s product website for detailed information. Align is a trademark of Proctor and Gamble.

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provitalize

researched

Pros

Title

High CFU Count

Vegan-Friendly and GMO-Free

Cons

Title

Limited probiotic strains

Very Expensive for Minimal Strain Diversity

Does Not Contain Prebiotics

Plastic bottles

User complaints results not achieved

Poor Better Business Bureau (BBB) Rating

Provitalize by Better Body Co. suggests they can support digestive health, weight management, and the relief of hot flashes for menopausal women. While we liked that the product contains 68 Billion CFUs, we were disappointed to see no prebiotics and a lack of strain diversity.

Provitalize has three clinically studied strains, only one of which, L. Gasseri, is on our top-6 strains list. Compare that to the top-rated brand on our list, with 16 unique clinically studied strains, including all three of Provitalize’s probiotic strains.

This brand uses a considerable amount of marketing hype and aggressive claims, along with their 41 complaints on Better Business Bureau (BBB) in the last year, which gives us some pause for concern. While some users have reported benefits from taking Provitalize, we found many users who reported no results. We recommend avoiding brands with claims that seem too good to be true. Choose a formula with a variety of probiotic strains, including prebiotics, shown in studies to help support proper microbiome balance and digestive and immune system support.

* Please refer to the manufacturer’s product website for detailed information. Provitalize is a registered trademark of Maneuver Marketing Pte. Ltd

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